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Sexually: Most germs that cause NGU can be passed during sex (vaginal, anal or oral) that involves direct mucous membrane contact with an infected person.

Nonsexual: These causes of NGU may include: urinary tract infections, an inflamed prostate gland due to bacteria (bacterial prostatitis), a narrowing or closing of the tube in the penis (urethral stricture), a tightening of the foreskin so that it cannot be pulled back from the head of the penis (phimosa), the result of a process such as inserting a tube into the penis (catheterization),

Perinatal: During birth, infants may be exposed to the germs causing NGU in passage through the birth canal. This may cause the baby to have infections in the eyes (conjunctivitis), ears, and lungs (pneumonia).

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